Developed by the Honda Racing Corporation in 2006, the Honda RC212V participated in is first race the very next year. It was named so as the word RC212V stands for, 

RC = Honda's prefix for 4-stroke motorcycles

212 =  second bike of the 21st century

V = V engine

With a liquid-cooled 4-stroke 800 cc engine this bike participated in several races that included drivers such as S Nakano, Marco Melandri, Carlos Checa, and Toni Elías. This bike under Team Honda Gresini had Toni Elias riding one.